Recombinant Human CD161 His Protein

Novus Biologicals | Catalog # NBP2-23169

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
View all CD161 Proteins and Enzymes »

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 67-225 of Human CD161

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMQKSSIE KCSVDIQQSR NKTTERPGLL NCPIYWQQLR EKCLLFSHTV NPWNNSLADC STKESSLLLI RDKDELIHTQ NLIRDKAILF WIGLNFSLSE KNWKWINGSF LNSNDLEIRG DAKENSCISI SQTSVYSEYC STEIRWICQK ELTPVRNKVY PDS

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CD161 His Protein

SDS-PAGE: Recombinant Human CD161 His Protein [NBP2-23169]

SDS-PAGE: Recombinant Human CD161 His Protein [NBP2-23169]

SDS-Page: Recombinant Human CD161 Protein [NBP2-23169]

Formulation, Preparation, and Storage

NBP2-23169
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD161

Killer cell lectin-like receptor subfamily B member 1, also known as KLRB1, plays an inhibitory role on natural killer (NK) cells cytotoxicity. Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. Recombinant human KLRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Alternate Names

CD161, CLEC5B, KLRB1, Ly59, NKR, NKRP1, NKRP1A

Gene Symbol

KLRB1

Additional CD161 Products

Product Documents for Recombinant Human CD161 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human CD161 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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