CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

Novus Biologicals | Catalog # NBP2-75907

Novus Biologicals

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Block/Neutralize, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Human IgG1 kappa Clone # hu5c8 (Ruplizumab)

Format

Azide and BSA Free
View all CD40 Ligand/TNFSF5 Primary Antibodies »

Product Specifications

Immunogen

Human CD40L

Specificity

The antibody binds to CD40L with an IC50 of 0.845 ug/ml.

Clonality

Monoclonal

Host

Human

Isotype

IgG1 kappa

Scientific Data Images for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

Western Blot: CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab))Azide and BSA Free [NBP2-75907]

Western Blot: CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab))Azide and BSA Free [NBP2-75907]

Western Blot: CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) [NBP2-75907] - Rat spleen (lane 1), rat muscle (lane 2), rat bladder (lane 3), human breast tumour (lane 4) and human thyroid tumour (lane 5) samples were resolved on a 10% SDS PAGE gel and blots probed with NBP2-75907 at 1 ug/ml before being detected by a secondary antibody. The expected band size (29 kDa) is seen in the human-derived samples, as well as bands corresponding to dimers and other multimers.

Applications for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Background: CD40 Ligand/TNFSF5

CD40L is the ligand for CD40, a member of the tumor necrosis factor (TNF) receptor superfamily. CD40L is expressed mainly on activated CD4+ T-lymphocytes as a single-pass type II membrane protein. Proteolytic processing of the membrane form results in a soluble secreted form of CD40L.

Alternate Names

CD154, CD40L, CD40LG, gp39, TNFSF5, TRAP

Gene Symbol

CD40LG

Additional CD40 Ligand/TNFSF5 Products

Product Documents for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for CD40 Ligand/TNFSF5 Antibody (hu5c8 (Ruplizumab)) - Azide and BSA Free

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  • Q: I am looking for paired ABs for use in detecting CD40L (rat) by ELISA. Do you have such a reagent(s) available?

    A:

    Unfortunately we currently do not have any CD40 Ligand antibody pairs that have been validated in Rat. The only antibody pairs we offer for CD40L are validated in Human. I apologize for this inconvenience. If you would be interested in testing one of our products in Rat I'd like to invite you to participate in our Innovators Reward Program. Please contact us at innovators@novusbio.com with any questions regarding this program.

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