CD5 Antibody Pair [HRP]

Novus Biologicals | Catalog # NBP2-79576

Novus Biologicals
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Key Product Details

Assay Type

Sandwich ELISA

Assay Range

12.5-800 pg/ml (example only; lot dependent)

Sensitivity

12.5 pg/ml (example only; lot dependent)

Reactivity

Mouse
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Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Mouse CD5.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for CD5 Antibody Pair [HRP]

Sandwich ELISA: CD5 Antibody Pair [HRP] [NBP2-79576] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for CD5 Antibody Pair [HRP]

  • Rabbit Monoclonal Capture Antibody
  • Rabbit Polyclonal Detection Antibody (HRP-conjugated): (Catalog # NBP2-89430)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: CD5

In humans, CD5 is a 55kDa T lymphocyte single chain transmembrane glycoprotein. It is present on all mature T lymphocytes, on most thymocytes and on many T cell leukemias and lymphomas. It reacts with a subpopulation of activated B cells. CD5/Lyt1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B cell antigen CD72. The frequency of CD5+ B cells exhibits strain dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B1 cells. Binding of CD5 on the T cell surface can augment alloantigen or mitogen induced lymphocyte proliferation and induces increased cytosolic free calcium, IL2 secretion, and IL2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T cell and B cell receptors.

Alternate Names

CD5

Gene Symbol

CD5

Additional CD5 Products

Product Documents for CD5 Antibody Pair [HRP]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CD5 Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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