CD79B Antibody [ADC] - (Iladatuzumab Vedotin, Research Grade)

Novus Biologicals | Catalog # NBP3-44513

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

ADC

Antibody Source

Monoclonal Human IgG1
View all CD79B Primary Antibodies »

Product Specifications

Immunogen

CD79B (Uniprot: P40259)

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Theoretical MW

145 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

This product is an Antibody-Drug Conjugate (ADC) for Research Use Only (RUO).

Iladatuzumab Vedotin is an ADC consisting of a CD79B-directed antibody and Monomethyl auristatin E (MMAE) used for the study of non-Hodgkin's lymphoma.

This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for CD79B Antibody [ADC] - (Iladatuzumab Vedotin, Research Grade)

Hu CD79B mAb [ADC] - (Iladatuzumab Vedotin)

ELISA: Hu CD79B mAb [ADC] - (Iladatuzumab Vedotin) [NBP3-44513]

Immobilized human CD79B His at 2 ug/mL can bind CD79B, EC50 is 0.01675 ug/mL.
Hu CD79B mAb [ADC] - (Iladatuzumab Vedotin)

Flow Cytometry: Hu CD79B mAb [ADC] - (Iladatuzumab Vedotin) [NBP3-44513]

Human CD79B HEK293 Cell Line were stained with CD79B and negative control protein respectively, washed and then followed by PE and analyzed with FACS,The EC50 is 0.13 mug/mL.

Applications for CD79B Antibody [ADC] - (Iladatuzumab Vedotin, Research Grade)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer
Spectra Viewer

Flow Cytometry Panel Builder

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Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.

Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
  • Spillover Popups - Visualize the spectra of individual fluorochromes
  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Flow Cytometry

Formulation, Preparation, and Storage

Purification

> 90% by SDS-PAGE and HPLC

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: CD79B

Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79alpha/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (1)

Alternate Names

B29, CD79B, IGB

Additional CD79B Products

Product Documents for CD79B Antibody [ADC] - (Iladatuzumab Vedotin, Research Grade)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for CD79B Antibody [ADC] - (Iladatuzumab Vedotin, Research Grade)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

B Cell Activation

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Protocols

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FAQs

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