CELT-211

Tocris Bioscience | Catalog # 7953

Fluorescent serotonin 5HT2B receptor ligand for HTS
Tocris Bioscience

Key Product Details

Description

Fluorescent serotonin 5HT2B receptor ligand for HTS

Wavelength

Excitation = 589 nm, Emission = 616 nm
View all Fluorescent Receptor Probes »

Product Description

CELT-211 is a potent and selective fluorescent h5HT2B serotonin receptor ligand. It shows full selectivity for h5HT2B over h5HT2A, h5HT2C (Ki values is 56.3 nM for h5HT2B receptors in radioligand binding assay). Excitation and emission maxima (λ) are 589 and 616 nm, respectively. Wavelengths are compatible with use as an acceptor dye in TR-FRET assays, together with the CoraFluor™ 1 (Cat. No. 7920) TR-FRET donor.

Add 82 μL of assay buffer containing 1% of DMSO to obtain a 100 μM stock solution, and use 250 nM as a working concentration.

Scientific Data Images for CELT-211

Application of CELT-211 in CHO cells expressing the human 5HT2BR.

Application of CELT-211 in CHO cells expressing the human 5HT2BR.

CHO cells expressing the human 5HT2BR labelled with CELT-211 (pink) at 56 nM and Hoechst 33342 (blue) (catalog # 5117) without (A) or with (B) 5-HT (50 µM) preincubation.

Licensing Information

Sold under license from Celtarys Research

Optical Data

λabs 589 nm
λem 616 nm
Application Time-resolved fluorescence energy transfer (TR-FRET)

Spectra Viewer

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Product Specifications for CELT-211

Molecular Weight

1330.22

Storage

Store at -20°C

Purity

≥95% (HPLC)

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

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Product Documents for CELT-211

Certificate of Analysis

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Product Specific Notices for CELT-211

For research use only

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