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CELT-211 | 5-HT2B
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Description: Fluorescent serotonin 5HT2B receptor ligand for HTS

Purity: ≥95%

Product Details

Biological Activity

CELT-211 is a potent and selective fluorescent h5HT2B serotonin receptor ligand. It shows full selectivity for h5HT2B over h5HT2A, h5HT2C (Ki values is 56.3 nM for h5HT2B receptors in radioligand binding assay). Excitation and emission maxima (λ) are 589 and 616 nm, respectively. Wavelengths are compatible with use as an acceptor dye in TR-FRET assays, together with the CoraFluor™ 1 (Cat. No. 7920) TR-FRET donor.

Add 82 μL of assay buffer containing 1% of DMSO to obtain a 100 μM stock solution, and use 250 nM as a working concentration.

Scientific Data

Fluorescence Imaging Application of CELT-211 in CHO cells expressing the human 5HT<sub>2B</sub>R. View Larger

Application of CELT-211 in CHO cells expressing the human 5HT2BR. CHO cells expressing the human 5HT2BR labelled with CELT-211 (pink) at 56 nM and Hoechst 33342 (blue) (catalog # 5748) without (A) or with (B) 5-HT (50 µM) preincubation.

Optical Data for CELT-211

λabs 589 nm
λem 616 nm
Application Time-resolved fluorescence energy transfer (TR-FRET)

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

Spectral Viewer

Technical Data

Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from Celtarys Research

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).


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