CeMMEC1

Key Product Details

Product Description

CeMMEC1 is a TAF1 inhibitor (Kd = 1.8 μM, IC₅₀ = 900 nM). CeMMEC1 impairs cell viability in combination with (+)-JQ1 (Cat. No. 4499) and inhibits proliferation of THP-1 and H23 lung adenocarcinoma cells.

Product Specifications for CeMMEC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for CeMMEC1

The following data is based on the product molecular weight 336.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.97 mL	14.87 mL	29.73 mL
5 mM	0.59 mL	2.97 mL	5.95 mL
10 mM	0.30 mL	1.49 mL	2.97 mL
50 mM	0.06 mL	0.30 mL	0.59 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Sdelci Mapping the chemical chromatin reactivation landscape identifies BRD 4-TAtaF1 cross-talk. Nat.Chem.Biol. 2016 PMID: 27159579

Product Documents for CeMMEC1