Cerebellin-2 (CBLN2) is an approximately 25 kDa glycoprotein in the Cerebellin family of C1q- and TNF-related proteins. It contains a potential membrane-associating segment but may also be secreted. It contains one C1q-like domain in its extracellular region. Cerebellin-2 expression is developmentally regulated in the cerebellum, neocortex, sensory neurons of the dorsal root ganglion and spinal cord, and adrenal cortex. It associates with Cerebellin-1 which is involved in the formation and maintenance of synapses in the cerebellum. Within the ectodomain (aa 50-224), Human Cerebellin-2 shares 99% aa sequence identity with mouse and rat Cerebellin-2.
Cerebellin-2 Antibody (704330) [Janelia Fluor® 646]
Novus Biologicals | Catalog # FAB7044J
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Janelia Fluor 646
Antibody Source
Monoclonal Mouse IgG2B Clone # 704330
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Product Specifications
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Cerebellin-2
Arg50-Leu224
Accession # Q8IUK8
Arg50-Leu224
Accession # Q8IUK8
Specificity
Detects human Cerebellin-2 in direct ELISAs and Western blots.
In direct ELISAs and Western blots, no
cross-reactivity with recombinant human Cerebellin-1, -3, or -4 is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for Cerebellin-2 Antibody (704330) [Janelia Fluor® 646]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Cerebellin-2
Alternate Names
CBLN2, Cerebellin2
Gene Symbol
CBLN2
Additional Cerebellin-2 Products
Product Documents for Cerebellin-2 Antibody (704330) [Janelia Fluor® 646]
Product Specific Notices for Cerebellin-2 Antibody (704330) [Janelia Fluor® 646]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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