CETP Antibody

Novus Biologicals | Catalog # NBP3-11019

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all CETP Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence GNAHACSKGTSHEA, from the N Terminus of the protein sequence according to NP_000069.2; NP_001273014.1.

Epitope

GNAHACSKGTSHEA

Specificity

This antibody is expected to recognise isoform s1 and 2.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Scientific Data Images for CETP Antibody

Western Blot: CETP Antibody [NBP3-11019]

Western Blot: CETP Antibody [NBP3-11019]

Western Blot: CETP Antibody [NBP3-11019] - Staining of HepG2 cell lysate (A) and Negative control Caco-2 cell lysate (B) (35 ug protein in RIPA buffer). Antibody at 0.3 ug/mL. Detected by chemiluminescence.

Applications for CETP Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:64000

Western Blot

0.3 - 1 ug/mL
Application Notes
Western blot: Approx 48kDa band observed in lysates of cell line HepG2 (calculated MW of 47.9kDa according to NP_001273014.1. Primary incubation 1 hour at room temperature. Negative Control: CaCo-2 cell lysate.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 degrees C. Avoid freeze/thaw cycles.

Background: CETP

It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

Long Name

Cholesteryl Ester Transfer Protein

Alternate Names

BPIFF, HDLCQ10, Lipid Transfer Protein I

Gene Symbol

CETP

Additional CETP Products

Product Documents for CETP Antibody

Certificate of Analysis

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Product Specific Notices for CETP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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