Coagulation Factor XI Antibody (2H8) - Azide and BSA Free

Novus Biologicals | Catalog # H00002160-M01

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA, Sandwich ELISA, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2H8

Format

Azide and BSA Free
View all Coagulation Factor XI Primary Antibodies »

Product Specifications

Immunogen

F11 (NP_000119, 286 a.a. ~ 385 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKIK

Specificity

F11 - coagulation factor XI (plasma thromboplastin antecedent)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Coagulation Factor XI Antibody (2H8) - Azide and BSA Free

Western Blot: Coagulation Factor XI Antibody (2H8) [H00002160-M01]

Western Blot: Coagulation Factor XI Antibody (2H8) [H00002160-M01]

Western Blot: Coagulation Factor XI Antibody (2H8) [H00002160-M01] - Analysis of F11 expression in transfected 293T cell line by F11 monoclonal antibody (M01), clone 2H8.Lane 1: F11 transfected lysate(70.1 KDa).Lane 2: Non-transfected lysate.
Immunoprecipitation: Coagulation Factor XI Antibody (2H8) [H00002160-M01]

Immunoprecipitation: Coagulation Factor XI Antibody (2H8) [H00002160-M01]

Immunoprecipitation: Coagulation Factor XI Antibody (2H8) [H00002160-M01] - Analysis of F11 transfected lysate using anti-F11 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with F11 MaxPab rabbit polyclonal antibody.
Sandwich ELISA: Coagulation Factor XI Antibody (2H8) [H00002160-M01] - Detection limit for recombinant GST tagged F11 is approximately 10ng/ml as a capture antibody.

Applications for Coagulation Factor XI Antibody (2H8) - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Coagulation Factor XI

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.

Alternate Names

coagulation factor XI, EC 3.4.21, EC 3.4.21.27, FXIPlasma thromboplastin antecedent, MGC141891, PTA

Entrez Gene IDs

2160 (Human)

Gene Symbol

F11

OMIM

264900 (Human)

UniProt

NP_000119 (Human)

Additional Coagulation Factor XI Products

Product Documents for Coagulation Factor XI Antibody (2H8) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Coagulation Factor XI Antibody (2H8) - Azide and BSA Free

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

No product specific FAQs exist for this product.

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Associated Pathways

Blood Coagulation Signaling Pathways Blood Coagulation Signaling Pathway Thumbnail