Catalog Number: 2294
Chemical Name: 3'-Deoxyadenosine
Biological Activity
Nucleoside analog that acts as an anticancer and antifungal agent. Can be converted to 3'-deoxyadenosine triphosphate (3'-dATP), which inhibits ATP-dependent DNA synthesis. Inhibits growth of various tumor cells in vitro.
Technical Data
  • M.Wt:
    251.24
  • Formula:
    C10H13N5O3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Desiccate at +4°C
  • CAS No:
    73-03-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The synthesis of 3'-dATP and its use as an inhibitor of ATP-dependent DNA synthesis in toluene-treated Escherichia coli.
    Gumport and Edelhei et al.
    Biochemistry, 1976;15:2804
  2. Antifungal activity of 3'-deoxyadenosine (cordycepin).
    Sugar and McCaffrey
    Antimicrob.Agents Chemother., 1998;42:1424
  3. Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotidyl transferase-positive (TdT+) leukemic cells.
    Kodama et al.
    Biochem.Pharmacol., 2000;59:273

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