csl/RBPJK Antibody (S05-6G4)

Novus Biologicals | Catalog # NBP3-19759

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S05-6G4 expressed in HEK293
View all CSL Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human csl/RBPJK (Uniprot # Q06330)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for csl/RBPJK Antibody (S05-6G4)

Western Blot: csl/RBPJK Antibody (S05-6G4) [NBP3-19759]

Western Blot: csl/RBPJK Antibody (S05-6G4) [NBP3-19759]

Western Blot: csl/RBPJK Antibody (S05-6G4) [NBP3-19759] - Western blot detection of csl/RBPJK in Rat Brain, C6 cell lysates using NBP3-19759 (1:1000 diluted). Predicted band size: 56kDa. Observed band size: 61kDa.

Applications for csl/RBPJK Antibody (S05-6G4)

Application
Recommended Usage

Western Blot

1/1000-1/5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CSL

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence

Long Name

Recombining Binding Protein Supressor of Hairless [CBF1, CSL]

Alternate Names

CBF1, IGKJRB1, KBF2, RBP-JK, RBPJ, RBPSUH

Gene Symbol

RBPJ

Additional CSL Products

Product Documents for csl/RBPJK Antibody (S05-6G4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for csl/RBPJK Antibody (S05-6G4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Dendritic Cell Development
Notch Pathway

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