CTCE 9908
1 Image
Description: CXCR4 antagonist; antitumor
Purity: ≥95%
Biological Activity
CTCE 9908 is a CXCR4 antagonist; induces mitotic catastrophe in ovarian cancer cells. Displays additive cytotoxic effects when given with taxol (Cat. No. 1097). Enhances the efficacy of docetaxel (Cat. No. 4056) in a mouse model.Technical Data
M.Wt:
1927.27
Formula:
C86H147N27O23
Sequence:
KGVSLSYRK KGVSLSYR*
(Modifications: Amide bridge = 9-8*, Lys-9 = C-terminal amide)
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
1030384-98-5
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
An antagonist of the chemokine receptor CXCR4 induces mitotic catastrophe in ovarian cancer cells.
Kwong et al.
Mol.Cancer Ther., 2009;8:1893 -
The many facets of SDF-1alpha, CXCR4 agonists and antagonists on hematopoietic progenitor cells.
Faber et al.
J.Biomed.Biotechnol., 2007;2007:26065 -
CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti-VEGF treatment or doce. in a transgenic mouse model.
Hassan et al.
Int.J.Cancer., 2011;129:225
Product Datasheets
Or select another batch:
Reconstitution Calculator
Molarity Calculator
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Peptide FAQsVersaClone cDNA Plasmids
Reviews for CTCE 9908
There are currently no reviews for this product. Be the first to review CTCE 9908 and earn rewards!
Have you used CTCE 9908?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris Bioscience is the leading supplier of novel and exclusive
tools for
life science research with over 30 years' experience in the
industry.
Tocris is a Bio-Techne brand.
