CXCR1, also known as IL-8RA and CD181, is an approximately 60 kDa 7TM glycoprotein that functions as a receptor for the chemokine CXCL8/IL-8. It is expressed on neutrophils, monocytes, CD8 T cells, FoxP3+ CD4 Treg cells, mast cells, neuronal and glial cells, vascular endothelial cells, and melanoma. CXCR1 forms homodimers and heterodimers with CXCR2/IL-8RB. It can be cleaved from neutrophils in the lungs of cystic fibrosis patients to release fragments that promote CXCL8 production from airway epithelial cells. CXCR1 mediates neutrophil activation and chemotaxis to sites of inflammation as well as angiogenesis and melanoma invasiveness.
Human CXCR1/IL-8RA ELISA Kit (Colorimetric)
Novus Biologicals | Catalog # NBP3-06836
Key Product Details
Sample Type & Volume Required Per Well
Sensitivity
Assay Range
Product Specifications
Assay Type
Kit Type
Species
Specificity
Precision
Intra-Assay Precision (Precision within an assay) 4.99
Inter-Assay Precision (Precision between assays) 4.61
Recovery for Human CXCR1/IL-8RA ELISA Kit (Colorimetric)
Recovery
Linearity
Scientific Data Images for Human CXCR1/IL-8RA ELISA Kit (Colorimetric)
ELISA: Human CXCR1/IL-8RA ELISA Kit (Colorimetric) [NBP3-06836] -
ELISA: Human CXCR1/IL-8RA ELISA Kit (Colorimetric) [NBP3-06836] - Standard Curve ReferenceKit Contents for Human CXCR1/IL-8RA ELISA Kit (Colorimetric)
- Biotinylated Detection Ab Diluent
- Concentrated Biotinylated Detection Ab (100x)
- Concentrated HRP Conjugate (100x)
- Concentrated Wash Buffer (25x)
- HRP Conjugate Diluent
- Micro ELISA Plate (Dismountable)
- Plate Sealer
- Product Manual
- Reference Standard
- Sample Diluent
- Stop Solution
- Substrate Reagent
Preparation and Storage
Shipping
Stability & Storage
Background: CXCR1/IL-8RA
Long Name
Alternate Names
Gene Symbol
Additional CXCR1/IL-8RA Products
Product Documents for Human CXCR1/IL-8RA ELISA Kit (Colorimetric)
Certificate of Analysis
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Product Specific Notices for Human CXCR1/IL-8RA ELISA Kit (Colorimetric)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.
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