CYM 5442 hydrochloride

Tocris Bioscience | Catalog # 3601

Selective S1P1 receptor agonist
Tocris Bioscience

Key Product Details

Description

Selective S1P1 receptor agonist
View all Sphingosine-1-phosphate Receptor Agonists »

Product Description

CYM 5442 hydrochloride is a potent and selective S1P1 agonist in vitro (EC50 = 1.35 nM). Activates S1P1-mediated p42/p44 MAPK phosphorylation in CHO-K1 cells transfected with S1P1. Induces acute lymphopenia in mice. Brain penetrant.

Product Specifications for CYM 5442 hydrochloride

Molecular Weight

445.94

Formula

C23H27N3O4.HCl

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl amino) ethanol hydrochloride

CAS Number

1783987-80-3

PubChem ID

90488865

InChI Key

KMZLVDAVGXYZDA-UHFFFAOYSA-N

SMILES

OCCNC3CCC(C3=CC=C4)=C4C1=NOC(C2=CC(OCC)=C(OCC)C=C2)=N1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 44.59 100

Preparing Stock Solutions for CYM 5442 hydrochloride

The following data is based on the product molecular weight 445.94.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.24 mL 11.21 mL 22.42 mL
5 mM 0.45 mL 2.24 mL 4.48 mL
10 mM 0.22 mL 1.12 mL 2.24 mL
50 mM 0.04 mL 0.22 mL 0.45 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

Product Documents for CYM 5442 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CYM 5442 hydrochloride

For research use only

Related Research Areas

Bioactive Lipids and Receptors

Citations for CYM 5442 hydrochloride

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