Dkk-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of Dkk-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Dkk-1 inhibition is critical for bone formation and homeostasis. In addition, Dkk-1 can act as either a tumor suppressor or promoter of metastasis.
Cynomolgus Monkey Dkk-1 (XP_005565907) VersaClone cDNA
R&D Systems | Catalog # RDC2792
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Dkk-1
Long Name
Dickkopf-1
Alternate Names
Dkk1
Gene Symbol
DKK1
UniProt
Additional Dkk-1 Products
Product Documents for Cynomolgus Monkey Dkk-1 (XP_005565907) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Cynomolgus Monkey Dkk-1 (XP_005565907) VersaClone cDNA
For research use only
Related Research Areas
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Associated Pathways
