Cytokeratin 20 Antibody (E19-I)

Novus Biologicals | Catalog # NBP2-21840

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # E19-I
View all Cytokeratin 20 Primary Antibodies »

Product Specifications

Immunogen

Peptide derived from C-terminal region of human cytokeratin 20. Antibody recognizes the epitope between Val408 - Ile424.

Epitope

Val408 - Ile424

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

Scientific Data Images for Cytokeratin 20 Antibody (E19-I)

Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-I) [NBP2-21840]

Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-I) [NBP2-21840]

Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-l) [NBP2-21840] - Adenoma of the large intestine with expression of CK20. Formalin fixed, paraffin embedded human tissues (4 um sections) stained with anti - Cytokeratin 20 monospecific clonal antibody
Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-I) [NBP2-21840]

Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-I) [NBP2-21840]

Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-l) [NBP2-21840] - Colorectal adenocarcinoma with diffuse strong expression of CK20. Adenoma of the large intestine with expression of CK20 (D). Formalin fixed, paraffin embedded human tissues (4 um sections) stained with anti - Cytokeratin 20 monospecific clonal antibody
Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-I) [NBP2-21840]

Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-I) [NBP2-21840]

Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-l) [NBP2-21840] - Colorectal adenocarcinoma with diffuse strong expression of CK20. Adenoma of the large intestine with expression of CK20 (D). Formalin fixed, paraffin embedded human tissues (4 um sections) stained with anti - Cytokeratin 20 monospecific clonal antibody
Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-I) [NBP2-21840]

Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-I) [NBP2-21840]

Immunohistochemistry-Paraffin: Cytokeratin 20 Antibody (E19-l) [NBP2-21840] - Colorectal adenocarcinoma and normal epithelium of the large intestine mucosa with expression of CK20. Formalin fixed, paraffin embedded human tissues (4 um sections) stained with anti - Cytokeratin 20 monospecific clonal antibody

Applications for Cytokeratin 20 Antibody (E19-I)

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:100-1:200

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

20mM Tris-HCl (pH 8.0) and 20mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Cytokeratin 20

Intermediate-sized filament (IF) protein designated cytokeratin (CK) 1 is a major cellular protein of mature enterocytes and goblet cells commonly found in mucosal epithelium of the mammalian gastrointestinal tract (1). Results strongly suggest that transcriptional regulation of keratin genes in the intestinal epithelium occurs at the level of both immature and terminally differentiated epithelial cells, and is tightly regulated during both fetal development and crypt-to-villus differentiation of the intestinal epithelium (2). CK20 has recently been reported to be useful to distinguish between primary and metastatic lung adenocarcinoma. CK20 expression was significantly more prevalent in adenocarcinoma that originated in the GI tract than that of pulmonary or breast origin (3).

Alternate Names

CD20, CK20, CK-20, cytokeratin-20, K20cytokeratin 20, keratin 20, keratin, type I cytoskeletal 20, keratin-20, KRT21, MGC35423, Protein IT

Gene Symbol

KRT20

UniProt

P35900 (Human)

Additional Cytokeratin 20 Products

Product Documents for Cytokeratin 20 Antibody (E19-I)

Certificate of Analysis

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Product Specific Notices for Cytokeratin 20 Antibody (E19-I)

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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