DCG IV

Key Product Details

Product Description

DCG IV is a presynaptic depressant; highly potent agonist for group II mGlu receptors.

Licensing Information

Sold with the permission of Suntory Ltd.

Product Specifications for DCG IV

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for DCG IV

The following data is based on the product molecular weight 203.15.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

20 19 18 17 16 15 14 13 12 11 10 9 8 7 6 5 4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.92 mL	24.61 mL	49.22 mL
5 mM	0.98 mL	4.92 mL	9.84 mL
10 mM	0.49 mL	2.46 mL	4.92 mL
50 mM	0.10 mL	0.49 mL	0.98 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 199 publications citing the usage of this product.

• Ohfune Synthesis of L-2-(2,3-dicarboxycyclopropyl)-glycines. Novel conformationally restricted glutamate analogues. Bioorg.Med.Chem.Lett.
• Cartmell Characterization of [³H]-(2S,2'R,3'R)-2-(2',3'-dicarboxycyclopropyl)glycine ([³H]-DCG IV) binding to metabotropic mGlu₂ receptor-transfected cell membranes. Br.J.Pharmacol. 1998 PMID: 9504391
• Ishida A novel metabotropic receptor agonist: marked depression of monosynaptic excitation in the isolated rat spinal cord. Br.J.Pharmacol. 1993 PMID: 8401927
• Brabet Comparative effect of L-CCG-I, DCG-IV and γ-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes. Neuropharmacology 1998 PMID: 9833633

Product Documents for DCG IV