DcR3/TNFRSF6B Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-13460

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all DcR3/TNFRSF6B Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: RDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DcR3/TNFRSF6B Antibody - BSA Free

Immunohistochemistry-Paraffin: DcR3/TNFRSF6B Antibody [NBP2-13460]

Immunohistochemistry-Paraffin: DcR3/TNFRSF6B Antibody [NBP2-13460]

Immunohistochemistry-Paraffin: DcR3 Antibody [NBP2-13460] Staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal and glial cells.
DcR3/TNFRSF6B Antibody - BSA Free Immunohistochemistry: DcR3/TNFRSF6B Antibody - BSA Free [NBP2-13460]

Immunohistochemistry: DcR3/TNFRSF6B Antibody - BSA Free [NBP2-13460]

Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.
DcR3/TNFRSF6B Antibody - BSA Free Immunohistochemistry: DcR3/TNFRSF6B Antibody - BSA Free [NBP2-13460]

Immunohistochemistry: DcR3/TNFRSF6B Antibody - BSA Free [NBP2-13460]

Staining of human colorectal cancer shows moderate cytoplasmic positivity in tumor cells.
DcR3/TNFRSF6B Antibody - BSA Free Immunohistochemistry: DcR3/TNFRSF6B Antibody - BSA Free [NBP2-13460]

Immunohistochemistry: DcR3/TNFRSF6B Antibody - BSA Free [NBP2-13460]

Staining of human pancreas shows no cytoplasmic positivity in exocrine glandular cells as expected.
DcR3/TNFRSF6B Antibody - BSA Free Immunohistochemistry: DcR3/TNFRSF6B Antibody - BSA Free [NBP2-13460]

Immunohistochemistry: DcR3/TNFRSF6B Antibody - BSA Free [NBP2-13460]

Staining of human cerebral cortex shows strong cytoplasmic positivity in neurons.

Applications for DcR3/TNFRSF6B Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DcR3/TNFRSF6B

DcR3 belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.

Long Name

Decoy Receptor 3

Alternate Names

M68, TNFRSF6B, TR6

Gene Symbol

TNFRSF6B

Additional DcR3/TNFRSF6B Products

Product Documents for DcR3/TNFRSF6B Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for DcR3/TNFRSF6B Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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