DDR1 Antibody - BSA Free

Novus Biologicals | Catalog # NB110-39041

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Monkey, Primate

Predicted:

Bovine (95%), Canine (95%), Chimpanzee (100%), Equine (95%), Hamster (95%), Mouse (95%), Rabbit (95%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all DDR1 Primary Antibodies »

Product Specifications

Immunogen

Synthetic 20 amino acid peptide from N-terminus of human DDR1.

Epitope

N-terminal region of human.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Zebrafish (80%).

Localization

Plasma membrane. Single-pass type I membrane protein.

Specificity

Human DDR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for DDR1 Antibody - BSA Free

Immunohistochemistry-Paraffin: DDR1 Antibody - BSA Free [NB110-39041]

Immunohistochemistry-Paraffin: DDR1 Antibody - BSA Free [NB110-39041]

Immunohistochemistry-Paraffin: DDR1 Antibody - BSA Free [NB110-39041] - Analysis of anti-DDR1 antibody with human decidual cells at concentration 15-20 ug/ml.

Applications for DDR1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

15 - 20 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: DDR1

DDR1 is a DDR/TKT type protein kinase. DDR1 is activated by various types of collagen, including types I through IV. Binding of collagen to DDR1 protein results in autophosphorylation and a delayed but sustained tyrosine kinase activation. DDR1 may function in cell-to-cell interaction or recognition. At least three mRNA variants, resulting in different protein isoforms of 875, 913 and 919 amino acids, have been reported. DDR1 protein has been shown to be over expressed in human breast, ovarian, esophageal and pediatric brain tumors.

Long Name

Discoidin Domain Receptor 1

Alternate Names

CAK, CD167a, RTK6, TrkE

Entrez Gene IDs

780 (Human)

Gene Symbol

DDR1

Additional DDR1 Products

Product Documents for DDR1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DDR1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for DDR1 Antibody - BSA Free

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  • Q: I was wondering if you offer, or are planning on offering, any antibodies targeted to specific phosphorylation sites on the receptor tyrosine kinase DDR1.

    A: At this time we do not offer and DDR1 antibodies specific for certain phosphorylation states.

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