Dectin-1/CLEC7A Antibody

Novus Biologicals | Catalog # NBP1-45514

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all Dectin-1/CLEC7A Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide surrounding amino acid 161 of human Dectin-1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

27.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab286157)

Scientific Data Images for Dectin-1/CLEC7A Antibody

Western Blot: Dectin-1/CLEC7A Antibody [NBP1-45514]

Western Blot: Dectin-1/CLEC7A Antibody [NBP1-45514]

Western Blot: Dectin-1/CLEC7A Antibody [NBP1-45514] - Analysis of Dectin-1 expression in lysate from rat kidney (Lane 1), 3T3 cells (Lane 2) and Jurkat cells (Lane 3 & 4).

Applications for Dectin-1/CLEC7A Antibody

Application
Recommended Usage

Western Blot

0.5 - 4 ug/mL

Reviewed Applications

Read 2 reviews rated 4.5 using NBP1-45514 in the following applications:

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2), 30% glycerol, 0.5% BSA

Preservative

0.01% Thimerosal

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Dectin-1/CLEC7A

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Alternate Names

CD369, CLEC7A, CLECSF12, Dectin1

Entrez Gene IDs

64581 (Human)

Gene Symbol

CLEC7A

UniProt

Q9BXN2 (Human)

Additional Dectin-1/CLEC7A Products

Product Documents for Dectin-1/CLEC7A Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Dectin-1/CLEC7A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Citations for Dectin-1/CLEC7A Antibody

Customer Reviews for Dectin-1/CLEC7A Antibody (2)

4.5 out of 5
2 Customer Ratings
5 Stars
50%
4 Stars
50%
3 Stars
0%
2 Stars
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1 Stars
0%

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  • Name: silvia agostini
    Application: Immunofluorescence
    Verified Customer | Posted 07/07/2014
    Dectin-1/CLEC7A Antibody NBP1-45514
  • Name: silvia agostini
    Application: Western Blot
    Sample Tested: human endothelial cell lysate (HMEC-1 and HUVEC)
    Species: Human
    Verified Customer | Posted 06/30/2014
    1:500 dilution in TBS-T 3% milk; human endothelial cells
    Dectin-1/CLEC7A Antibody NBP1-45514

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FAQs for Dectin-1/CLEC7A Antibody

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  • Q: I am looking for a human dectin-1 and 2 for western blot. How can I know if it works? Do you have any references from the literature that confirm your products? If yes-I'll be happy to read few articles who used your dectin-1 and it worked.

    A: Unfortunately, to the best of our knowledge, our dectin antibodies have not been cited in literature yet, and for the peace of your mind, my suggestion to you would be to make your decision based upon the validation images shown on datasheets. You may find our Dectin 1 and Dectin 2 antibodies suitable for WB application using these links. We stand by the quality of our products and all our products are 100% guaranteed. We are always there to help in case you face any trouble in generating your desired outcome out of the use of our products. Please let me know if I can help you with any other queries.

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