Desipramine hydrochloride

Key Product Details

Product Description

Desipramine hydrochloride is a tricyclic antidepressant that is a selective inhibitor of noradrenalin transporters (K_i values are 4, 61 and 78720 nM for NET, SERT and DAT transporters respectively).

Product Specifications for Desipramine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Desipramine hydrochloride

The following data is based on the product molecular weight 302.84.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

5 4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.30 mL	16.51 mL	33.02 mL
5 mM	0.66 mL	3.30 mL	6.60 mL
10 mM	0.33 mL	1.65 mL	3.30 mL
50 mM	0.07 mL	0.33 mL	0.66 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 35 publications citing the usage of this product.

• Zhao NE transporter regulation mediates the long-term behavioral effects of the antidepressant desipr. Neuropsychopharmacol.
• Torres Plasma membrane monoamine transporters: structure, regulation and function. Nat.Rev.Neurosci. 2003 PMID: 12511858

Product Documents for Desipramine hydrochloride