Desipramine hydrochloride

  ( 5 citations )    
Product Datasheet
Catalog Number:3067
Chemical Name:10-11-Dihydro-N-methyl-5H-dibenz(Z)[b,f]azepine-5-propanamine hydrochloride
Product Details
Citations (5)
Supplemental Products
Reviews
Biological Activity
Tricyclic antidepressant that is a selective inhibitor of noradrenalin transporters (Ki values are 4, 61 and 78720 nM for NET, SERT and DAT transporters respectively).
Technical Data
  • M.Wt:
    302.84
  • Formula:
    C18H22N2.HCl
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >99
  • Storage:
    Desiccate at +4°C
  • CAS No:
    58-28-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Desipramine hydrochloride include:

5 Citations: Showing 1 - 5
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  1. CD59 signaling and membrane pores drive Syk-dependent erythrocyte necroptosis.
    Authors: LaRocca Et al.
    Neuropsychopharmacology  2015;6:e1773
  2. Lateral diffusion of Gαs in the plasma membrane is decreased after chronic but not acute antidepressant treatment: role of lipid raft and non-raft membrane microdomains.
    Authors: Czysz Et al.
    Proc Natl Acad Sci U S A  2015;40:766
  3. Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis.
    Authors: Bucher Et al.
    J Cereb Blood Flow Metab  2014;34:1128
  4. Synergistic regulation of glutamatergic transmission by serotonin and norepinephrine reuptake inhibitors in prefrontal cortical neurons.
    Authors: Yuen Et al.
    J Biol Chem  2014;289:25177
  5. Changes in c-Fos Expression in the Forced Swimming Test: Common and Distinct Modulation in Rat Brain by Desipramine and Citalopram.
    Authors: Choi Et al.
    Korean J Physiol Pharmacol  2013;17:321

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