Desipramine hydrochloride

Catalog # Availability Size / Price Qty
Desipramine hydrochloride | CAS No. 58-28-6 | Adrenergic Transporter Inhibitors
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Description: Selective inhibitor of noradrenalin transporters

Chemical Name: 10-11-Dihydro-N-methyl-5H-dibenz(Z)[b,f]azepine-5-propanamine hydrochloride

Purity: ≥99%

Product Details
Citations (8)
Supplemental Products

Biological Activity

Desipramine hydrochloride is a tricyclic antidepressant that is a selective inhibitor of noradrenalin transporters (Ki values are 4, 61 and 78720 nM for NET, SERT and DAT transporters respectively).

Technical Data

Soluble to 100 mM in water
Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Plasma membrane monoamine transporters: structure, regulation and function.
    Torres et al.
    Nat.Rev.Neurosci., 2003;4:13
  2. NE transporter regulation mediates the long-term behavioral effects of the antidepressant desipr.
    Zhao et al.
    Neuropsychopharmacol., 2008;33:3190

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Citations for Desipramine hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Desipramine hydrochloride include:

8 Citations: Showing 1 - 8


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