(±)-Clopidogrel hydrochloride

Tocris Bioscience | Catalog # 2490

Selective P2Y12 antagonist
Tocris Bioscience

Key Product Details

Description

Selective P2Y12 antagonist

Alternative Names

Plavix
View all P2Y Receptor Antagonists »

Product Description

(±)-Clopidogrel hydrochloride is a selective, high affinity P2Y12 receptor antagonist (pKi = 6.9 for hP2Y12 receptor). Inhibits ADP-induced platelet aggregation; potent antithrombotic agent. Requires bioactivation, unlike PSB 0739.

Active Enantiomer also available.

Product Specifications for (±)-Clopidogrel hydrochloride

Molecular Weight

358.28

Formula

C16H16NO2SCl.HCl

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrochloride

CAS Number

130209-90-4

PubChem ID

22386150

InChI Key

XIHVAFJSGWDBGA-UHFFFAOYSA-N

SMILES

Cl.COC(=O)C(N1CCC2=C(C1)C=CS2)C1=C(Cl)C=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 35.83 100
Ethanol 35.83 100

Preparing Stock Solutions for (±)-Clopidogrel hydrochloride

The following data is based on the product molecular weight 358.28.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.79 mL 13.96 mL 27.91 mL
5 mM 0.56 mL 2.79 mL 5.58 mL
10 mM 0.28 mL 1.40 mL 2.79 mL
50 mM 0.06 mL 0.28 mL 0.56 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

  • Savi P2Y12, a new platelet ADP receptor, target of clopid. Biochem.Biophys.Res.Comm.
  • Savi and Herbert Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas.
  • Kugelgen Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 2006 PMID: 16257449

Product Documents for (±)-Clopidogrel hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (±)-Clopidogrel hydrochloride

For research use only

Related Research Areas

Bioactive Lipids and Receptors

Citations for (±)-Clopidogrel hydrochloride

Customer Reviews for (±)-Clopidogrel hydrochloride (1)

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  • P2Y12 antagonist
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 09/20/2018
    incubation and during assay

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