PSB 0739

Tocris Bioscience | Catalog # 3983

Highly potent P2Y12 antagonist
Tocris Bioscience

Key Product Details

Description

Highly potent P2Y12 antagonist
View all P2Y Receptor Antagonists »

Product Description

PSB 0739 is a highly potent P2Y12 receptor antagonist (Ki = 24.9 nM). Unlike clopidogrel (Cat. No. 2490), does not require bioactivation.

Licensing Information

Sold with the permission of the University of Bonn.

Product Specifications for PSB 0739

Molecular Weight

609.54

Formula

C26H17N3Na2O8S2

Storage

Desiccate at RT

Purity

≥95% (HPLC)

Chemical Name

1-Amino-9,10-dihydro-9,10-dioxo-4-[[4-(phenylamino)-3-sulfophenyl]amino]-2-anthracenesulfonic acid sodium salt

CAS Number

1052087-90-7

PubChem ID

44583582

InChI Key

QBLLYXXXOJUNCV-UHFFFAOYSA-L

SMILES

[Na+].[Na+].NC1=C(C=C(NC2=CC(=C(NC3=CC=CC=C3)C=C2)S([O-])(=O)=O)C2=C1C(=O)C1=CC=CC=C1C2=O)S([O-])(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 15.24 25

Preparing Stock Solutions for PSB 0739

The following data is based on the product molecular weight 609.54.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 6.56 mL 32.81 mL 65.62 mL
1.25 mM 1.31 mL 6.56 mL 13.12 mL
2.5 mM 0.66 mL 3.28 mL 6.56 mL
12.5 mM 0.13 mL 0.66 mL 1.31 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 55 publications citing the usage of this product.

Product Documents for PSB 0739

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PSB 0739

For research use only

Related Research Areas

Bioactive Lipids and Receptors

Customer Reviews for PSB 0739 (2)

4 out of 5
2 Customer Ratings
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50%
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  • Good inhibitor
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Cell Line/Tissue: phagocyte
    Verified Customer | Posted 06/06/2020
    H20; dilution 10 μM
    PSB 0739 3983
  • P2Y12 blocker
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: acute brain slice
    Verified Customer | Posted 01/30/2018
    Used to block P2Y12 in acute brain slices. Monitored was the motility of microglia. No significant effect was found.

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