Catalog Number: 3983
Chemical Name: 1-Amino-9,10-dihydro-9,10-dioxo-4-[[4-(phenylamino)-3-sulfophenyl]amino]-2-anthracenesulfonic acid sodium salt
Biological Activity
Highly potent P2Y12 receptor antagonist (Ki = 24.9 nM). Unlike clopidogrel (Cat. No. 2490), does not require bioactivation.
Technical Data
  • M.Wt:
    609.54
  • Formula:
    C26H17N3Na2O8S2
  • Solubility:
    Soluble to 25 mM in water
  • Purity:
    >95%
  • Storage:
    Desiccate at RT
  • CAS No:
    1052087-90-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of the University of Bonn.
Background References
  1. Development of a comprehensive set of P2 receptor pharmacological research compounds.
    Felix et al.
    Purinerg.Sig., 2011;8:101
  2. Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor.
    Hoffmann et al.
    J.Pharmacol.Exp.Ther., 2009;331:648
  3. High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.
    Baqi et al.
    J.Med.Chem., 2009;52:3784
Citations:

The citations listed below are publications that use Tocris products. Selected citations for PSB 0739 include:

2 Citations: Showing 1 - 2
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  1. Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system
    Authors: Takayama Et al.
    Scientific Reports 2016;6:30006
  2. Nucleolin down-regulation is involved in ADP-induced cell cycle arrest in S phase and cell apoptosis in vascular endothelial cells.
    Authors: Wang Et al.
    PLoS One 2014;9:e110101

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