Chemical Name: 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]aminoethyl-1,2-benzenediol hydrochloride
Biological ActivityDobutamine hydrochloride is a β1- and β2-adrenoceptor agonist with some action at the α1-adrenoceptor.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Dobutamine: positive inotropy by nonselective adrenoceptor agonism in isolated guinea pig and human myocardium.
Brown et al.
Naunyn Schmiedebergs Arch.Pharmacol., 1987;335:385
Characterization of the beta adrenoceptor subtype(s) mediating the positive inotropic effects of epinine, DA, dobutamine, denopamine and xamoterol in isolated human right atrium.
Deighton et al.
Citations for Dobutamine hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Dobutamine hydrochloride include:
3 Citations: Showing 1 - 3
Pericytes impair capillary blood flow and motor function after chronic spinal cord injury.
Authors: Li Et al.
Nat Med 2017;23:733
Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation.
Authors: Kaya Et al.
Biol Reprod 2009;329:350
Pharmacological characterization of the receptors involved in the beta-adrenoceptor-mediated stimulation of the L-type Ca2+ current in frog ventricular myocytes.
Authors: Skeberdis Et al.
Br J Pharmacol 1997;121:1277
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