Catalog Number: 0515
Chemical Name: 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]aminoethyl-1,2-benzenediol hydrochloride
Biological Activity
β1- and β2-adrenoceptor agonist with some action at the α1-adrenoceptor.
Technical Data
  • M.Wt:
    337.85
  • Formula:
    C18H23NO3.HCl
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Desiccate at RT
  • CAS No:
    49745-95-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References

  1. Kishimoto T et al.
    Leucocyte Typing VI. Garland Publishing Inc. London.
  2. Dobutamine: positive inotropy by nonselective adrenoceptor agonism in isolated guinea pig and human myocardium.
    Brown et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 1987;335:385
  3. Characterization of the beta adrenoceptor subtype(s) mediating the positive inotropic effects of epinine, dopamine, dobutamine, denopamine and xamoterol in isolated human right atrium.
    Deighton et al.
    J.Pharmacol.Exp.Ther., 1992;262:532
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Dobutamine hydrochloride include:

2 Citations: Showing 1 - 2
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  1. Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation.
    Authors: Kaya Et al.
    Biol Reprod 2009;329:350
  2. Pharmacological characterization of the receptors involved in the beta-adrenoceptor-mediated stimulation of the L-type Ca2+ current in frog ventricular myocytes.
    Authors: Skeberdis Et al.
    Br J Pharmacol 1997;121:1277

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