-adrenoceptor antagonist (pKi
values are 9.0, 8.5 and 8.4 for human α1B
receptors respectively). Displays antihypertensive activity.
Soluble to 75 mM in DMSO
Desiccate at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Evaluation of the pharmacological selectivity profile of α1 adrenoceptor antagonists at prostatic α1 adrenoceptors: binding functional and in vivo studies.
Kenny et al.
The α1-adrenoceptor antagonist profile of doxazosin: preclinical pharmacology.
Alabaster and Davey
Chiral selective effects of doxazosin enantiomers on blood pressure and urinaruy bladder pressure in anesthetized rats.
Ma et al.
Acta Pharmacol.Sinica, 2006;27:1423
The citations listed below are publications that use Tocris products. Selected citations for Doxazosin mesylate include:
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