Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Biotin

Antibody Source

Polyclonal Rabbit IgG
View all DUSP12 Primary Antibodies »

Product Specifications

Immunogen

Recognizes region between residues Between Between 1 and 50..

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for DUSP12 Antibody [Biotin]

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: DUSP12

DUSP12 is encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

Alternate Names

dual specificity phosphatase 12, dual specificity protein phosphatase 12, Dual specificity tyrosine phosphatase YVH1, DUSP1YVH1 protein-tyrosine phosphatase ortholog, EC 3.1.3.48, serine/threonine specific protein phosphatase, TDSP4, YVH1EC 3.1.3.16

Gene Symbol

DUSP12

Additional DUSP12 Products

Product Documents for DUSP12 Antibody [Biotin]

Certificate of Analysis

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Download SDS

Product Specific Notices for DUSP12 Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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