EDAR Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-84081

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all EDAR Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for EDAR Antibody - BSA Free

EDAR Antibody - BSA Free Immunohistochemistry-Paraffin: EDAR Antibody - BSA Free [NBP1-84081]

Immunohistochemistry-Paraffin: EDAR Antibody - BSA Free [NBP1-84081]

Staining of human liver shows no positivity in human liver as expected.
EDAR Antibody - BSA Free Immunohistochemistry-Paraffin: EDAR Antibody - BSA Free [NBP1-84081]

Immunohistochemistry-Paraffin: EDAR Antibody - BSA Free [NBP1-84081]

Staining of human tonsil shows strong membranous positivity in germinal center and non-germinal center cells.
EDAR Antibody - BSA Free Immunohistochemistry-Paraffin: EDAR Antibody - BSA Free [NBP1-84081]

Immunohistochemistry-Paraffin: EDAR Antibody - BSA Free [NBP1-84081]

Staining of human rectum shows strong cytoplasmic granular positivity in glandular cells.
EDAR Antibody - BSA Free Immunohistochemistry-Paraffin: EDAR Antibody - BSA Free [NBP1-84081]

Immunohistochemistry-Paraffin: EDAR Antibody - BSA Free [NBP1-84081]

Staining of human skin shows moderate cytoplasmic granular positivity in squamous epithelial cells.

Applications for EDAR Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EDAR

The EDAR gene encodes a 448 amino acid long, approximately 48 kDA tumor necrosis factor receptor superfamily member EDAR protein that monitors the activation of NF-kappa-B and JNK. It functions as a receptor for EDA isoform 1 but not for isoform 2. EDAR is critical for hair, teeth and other ectodermal derivatives development. EDAR participates in the TNF superfamily pathway, the integrated breast cancer pathway, and the cytokine-cytokine receptor interaction. It is known to interact with genes EDA, TRAF1, TRAF2, TRAF3, as well as EDARADD. Defects in EDAR cause ectodermal dysplasia 10A and 10B. EDAR is linked to hepatitis, immunodeficiency, osteosarcoma, hypotrichosis, tooth agenesis, breast cancer, Clouston syndrome, and ectodermal dysplasia.

Long Name

Ectodysplasin Receptor

Alternate Names

Anhidrotic ectodysplasin receptor 1, DLED3, Ectodermal dysplasia receptor, ectodysplasin 1, anhidrotic receptor, ectodysplasin A receptor, Ectodysplasin-A receptor, ED1R, ED5, EDA1R, EDA3EDA-A1 receptor, EDA-A1R, Edar, FLJ94390, HRM1, mouse, homolog of, tumor necrosis factor receptor superfamily member EDAR

Gene Symbol

EDAR

Additional EDAR Products

Product Documents for EDAR Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for EDAR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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