EIDD 1931

Catalog # Availability Size / Price Qty
7231/25
7231/5
EIDD 1931 | CAS No. 3258-02-4 | RNA/DNA Polymerase Inhibitors
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Description: Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleoside

Chemical Name: N-Hydroxycytidine

Purity: ≥98%

Product Details
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Biological Activity

EIDD 1931 is a viral RNA-dependent RNA polymerase (RdRP) inhibitor and broad spectrum antiviral nucleotide. Inhibits replication of a range of RNA viruses including influenza, Ebola, HCV, and human and zoonotic coronaviruses (IC50 values are 0.15 and 0.3 μM for inhibition of MERS-CoV and SARS-CoV-2 replication in vitro). Increases mutation rates and induces lethal mutagenesis in viral RNA. Also inhibits replication of mouse hepatitis virus with mutations conferring resistance to remdesivir (Cat. No. 7226).

Technical Data

M.Wt:
259.22
Formula:
C9H13N3O6
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in water
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
3258-02-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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