9 results for "RNA Polymerase Inhibitors" in Products
RNA Polymerase Inhibitors
RNA Polymerases Classification
In eukaryotes, there are four forms of RNA polymerase (I-IV), which are classified on the basis of the type of RNA they produce. RNA polymerase I (Pol I) makes a pre-ribosomal RNA (pre-rRNA 45S), which makes up ~50% of the RNA produced in a cell; RNA polymerase II (Pol II), which makes precursors of mRNAs, most snRNA and microRNAs; RNA polymerase III (Pol III), which makes tRNAs and rRNA 5S, as well as other small RNAs found in the cell. RNA polymerase IV is an ...
Inhibits RNA polymerase
| Chemical Name: | 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide |
| Purity: | ≥95% |
Inhibitor of DNA and RNA polymerase
| Chemical Name: | (1S)-5-Deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1.fwdarw.3)-O-2,6-dideoxy-β-D-lyxo-hexopyranosyl-(1.fwdarw.3)-2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose |
| Purity: | ≥95% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug
| Alternate Names: | GS-5734 |
| Chemical Name: | 2-Ethylbutyl (2S)-2-[[(S)-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate |
| Purity: | ≥98% |
Inhibitor of RNA polymerase II
| Chemical Name: | cyclo[L-Asparaginyl-4-hydroxy-L-prolyl-(R)-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic (4→8)-sulfide (R)-S-oxide |
| Purity: | ≥95% |
RNA polymerase I inhibitor; also p53 pathway activator
| Chemical Name: | N-[2-(Dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide |
| Purity: | ≥98% |
Viral RNA polymerase inhibitor
| Alternate Names: | T 705 |
| Chemical Name: | 6-Fluoro-3,4-dihydro-3-oxo-2-pyrazinecarboxamide |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide
| Chemical Name: | (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral
| Alternate Names: | BCX 4430 |
| Chemical Name: | (2S,3S,4R,5R)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3,4-pyrrolidinediol dihydrochloride |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleoside
| Chemical Name: | N-Hydroxycytidine |
| Purity: | ≥98% |
