Endomucin/Mucin -14 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-92150

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Endomucin Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EAANNSLVVTTTKPSITTPNTESLQKNVVTPTTGTTPKGTITNELLKMSLMSTATFLTSKDEGLKATTTDVRKNDSIISNVTVTSVTLPNAVSTLQSSKPKTETQSSIKTTEIP

Marker

pan-Endothelial Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Endomucin/Mucin -14 Antibody - BSA Free

Endomucin/Mucin -14 Antibody - BSA Free Immunohistochemistry: Endomucin/Mucin -14 Antibody - BSA Free [NBP1-92150]

Immunohistochemistry: Endomucin/Mucin -14 Antibody - BSA Free [NBP1-92150]

Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Applications for Endomucin/Mucin -14 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Endomucin

Endomucin (endothelial sialomucin; also Endomucin-1/2 and Mucin-14) is an 80 - 120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or anti-adhesive molecule.

Mouse Endomucin precursor is 261 amino acids in length. It is type I transmembrane protein that contains a 170 aa extracellular domain (ECD) (aa 21 - 190) and a 50 aa cytoplasmic region. Three splice variants exist in the ECD of Endomucin. One shows a deletion of aa 91 - 141, a second shows a one aa substitution for aa 91 - 129, and a third shows a one aa substitution for aa 129 - 142. Over aa 21 - 90, mouse Endomucin shares 60% and 30% aa identity with rat and human Endomucin, respectively.

Alternate Names

EMCN, EMCN2, MUC-14

Gene Symbol

EMCN

Additional Endomucin Products

Product Documents for Endomucin/Mucin -14 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Endomucin/Mucin -14 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Endomucin/Mucin -14 Antibody - BSA Free

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Protocols

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