Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Epac2 Primary Antibodies »

Product Specifications

Immunogen

EPAC2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human EPAC2. The immunogen is located within the first 50 amino acids of EPAC2. Amino Acid Squence: LDKRPLERSSEDVD

Specificity

At least two isoforms of EPAC2 are known to exist; this antibody will detect only the larger isoform. EPAC2 antibody is predicted to not cross-react with EPAC2

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Epac2 Antibody - BSA Free

Western Blot: Epac2 AntibodyBSA Free [NBP2-82089]

Western Blot: Epac2 AntibodyBSA Free [NBP2-82089]

Western Blot: Epac2 Antibody [NBP2-82089] - Western blot analysis of EPAC2 in rat liver tissue lysate with EPAC2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Epac2 Antibody - BSA Free

Immunohistochemistry: Epac2 Antibody - BSA Free [NBP2-82089] -

Immunohistochemistry: Epac2 Antibody - BSA Free [NBP2-82089] - Immunohistochemistry of EPAC3 in mouse liver tissue with EPAC3 antibody at 2.5 ug/mL.
Epac2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Epac2 Antibody - BSA Free [NBP2-82089] -

Immunocytochemistry/ Immunofluorescence: Epac2 Antibody - BSA Free [NBP2-82089] - Immunofluorescence of Epac2 in mouse liver tissue with Epac2 antibody at 20 ug/mL.

Applications for Epac2 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Epac2

Epac2, also known as Rap Guanine Nucleotide Exchange Factor (GEF) 4, is a guanine nucleotide exchange factor for RAP1A, RAP1B and RAP2A small GTPases. Studies have shown that EPAC2 has a significant role in the development of type 2 diabetes. EPAC2 has also been studied in relation to ataxia, neuronitis, osteoporosis and pancreatitis.

Long Name

Rap guanine nucleotide exchange factor 4

Alternate Names

cAMP-GEFII, CGEF2, EPAC 2, RAPGEF4

Gene Symbol

RAPGEF4

Additional Epac2 Products

Product Documents for Epac2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Epac2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

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