Chemical Name: (5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt
Biological ActivityEpoprostenol is an endogenous prostanoid that is a potent agonist at IP prostanoid receptors. Inhibits platelet aggregation and induces vasodilation.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
PGI2-receptors and molecular mechanisms in platelets and vasculature: state of the art.
Oliva and Nicosia
Comparison of anti-aggregatory effects of PGI2, PGI3 and ilo. on human and rabbit platelets.
Kobzar et al.
Citations for Epoprostenol
The citations listed below are publications that use Tocris products. Selected citations for Epoprostenol include:
2 Citations: Showing 1 - 2
Inhibition of profibrotic microRNA-21 affects platelets and their releasate.
Authors: Barwari Et al.
JCI Insight 2018;3
Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction.
Authors: Armstrong Et al.
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