Catalog Number: 2989
Alternate Names: Prostaglandin I2, Prostacyclin
Chemical Name: (5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt
Biological Activity
Endogenous prostanoid that is a potent agonist at IP prostanoid receptors. Inhibits platelet aggregation and induces vasodilation.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water and to 75 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at -80°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Comparison of anti-aggregatory effects of PGI2, PGI3 and iloprost on human and rabbit platelets.
    Kobzar et al.
    Cell.Physiol.Biochem., 2001;11:279
  2. PGI2-receptors and molecular mechanisms in platelets and vasculature: state of the art.
    Oliva and Nicosia
    Pharmacol.Res.Comm., 1987;19:735

The citations listed below are publications that use Tocris products. Selected citations for Epoprostenol include:

Showing Results 1 - 1 of 1

  1. Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction.
    Authors: Armstrong Et al.
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