ErbB2/Her2 Antibody Pair [HRP]

Novus Biologicals | Catalog # NBP2-79664

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Assay Type

Sandwich ELISA

Assay Range

24-1500 pg/ml (example only; lot dependent)

Sensitivity

24 pg/ml (example only; lot dependent)

Reactivity

Human
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Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Human ErbB2/Her2.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for ErbB2/Her2 Antibody Pair [HRP]

Sandwich ELISA: ErbB2/Her2 Antibody Pair [HRP] [NBP2-79664] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for ErbB2/Her2 Antibody Pair [HRP]

  • Rabbit Monoclonal Capture Antibody: (Catalog # NBP2-89187)
  • Rabbit Monoclonal Detection Antibody (HRP-conjugated): (Catalog # NBP2-89186)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: ErbB2/Her2

ErbB2/HER2 is one of the four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases (1). The kinase activity of ErbB2 can be activated without ligand if it is overexpressed, and by association with other ErbB proteins (2). Overexpression of ErbB2 is detected in almost 40% of human breast cancers (3). Binding of c-Cbl ubiquitin ligase to Tyr1112 of ErbB2 leads to poly-ubiquitination of ErbB2 and enhances its degradation (4). ErbB2 is one of the major targets for the treatment of breast cancer and other carcinomas.

Long Name

Receptor Tyrosine Protein Kinase ErbB2

Alternate Names

CD340, HER2, Neu Oncogene, NGL, TKR1

Gene Symbol

ERBB2

Additional ErbB2/Her2 Products

Product Documents for ErbB2/Her2 Antibody Pair [HRP]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ErbB2/Her2 Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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FAQs for ErbB2/Her2 Antibody Pair [HRP]

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  • Q: I am interested in getting antibodies for HER that would work in flow cytometry. Could you recommend some choices?

    A: A list of our ErbB2 antibodies validated for use in flow cytometry can be found here /productsearch/HER2#fq=common_name%3A%22ErbB2%2FHER2%22&fq=category%3A%22Primary%20Antibodies%22&fq=applications%3A%22Flow%20Cytometry%22

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