Factor VIII Antibody (5E9B2)

Novus Biologicals | Catalog # NBP1-51555

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 5E9B2
View all Factor VIII Primary Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of Factor VIII expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Factor VIII Antibody (5E9B2)

Western Blot: Factor VIII Antibody (5E9B2)BSA Free [NBP1-51555]

Western Blot: Factor VIII Antibody (5E9B2)BSA Free [NBP1-51555]

Western Blot: Factor VIII Antibody (5E9B2) [NBP1-51555] - Analysis using F8 mouse mAb against truncated Trx-F8 recombinant protein (1).

Applications for Factor VIII Antibody (5E9B2)

Application
Recommended Usage

ELISA

1:10000

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Ascites

Formulation

Ascites

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Factor VIII

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Alternate Names

AHF, Antihemophilic factor, coagulation factor VIII, procoagulant component, coagulation factor VIIIc, DXS1253E, F8Ccoagulation factor VIII, factor VIII F8B, FVIII, HEMAF8B, Procoagulant component

Gene Symbol

F8

Additional Factor VIII Products

Product Documents for Factor VIII Antibody (5E9B2)

Certificate of Analysis

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Product Specific Notices for Factor VIII Antibody (5E9B2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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