FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free

Novus Biologicals | Catalog # NBP3-43985

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL3638

Format

Azide and BSA Free
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Product Specifications

Immunogen

This antibody was generated using a recombinant protein sequence of P55899, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free

FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody [NBP3-43985]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody [NBP3-43985]

Staining of human skeletal muscle shows absence of immunoreactivity (negative control).
FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody [NBP3-43985]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody [NBP3-43985]

Staining of human liver shows strong immunoreactivity in Kupffer cells.
FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody [NBP3-43985]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody [NBP3-43985]

Staining of human lymph node shows strong positivity in a subset of lymphoid cells.
FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody [NBP3-43985]

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody [NBP3-43985]

Staining of human placenta shows immunoreactivity in a subset of lymphoid cells.

Applications for FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
IHC-Paraffin HIER pH6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: FCRN

The FCGRT gene encodes a 365 amino acid long, 39 kDA IgG receptor FcRn large subunit p51 protein that transfers immunoglobulin G antibodies across the placenta from mother to fetus, as well as functions to protect the antibody from degradation. FCGRT interacts with genes CA6, ELANE, AZGP1, B2M, and ALB. It has been linked to diseases such as: lupus, nephritis, leukemia, arthritis, immunodeficiency, epidermolysis bullosa acquisita, persistent fetal circulation syndrome, and pemphigus.

Long Name

Neonatal Fc Receptor

Alternate Names

FCGRT

Gene Symbol

FCGRT

Additional FCRN Products

Product Documents for FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

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Protocols

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FAQs

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