FGF-17 Antibody [DyLight 405]

Name: FGF-17 Antibody [DyLight 405]
Brand: Novus Biologicals
SKU: AF319E
Price: 549 USD
Availability: InStock

Novus Biologicals | Catalog # AF319E

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Neutralization

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Polyclonal Goat IgG

View all FGF-17 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human FGF-17
Thr23-Thr216
Accession # O60258

Specificity

Detects human FGF-17 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human (rh) FGF-8b and recombinant mouse FGF-8c is observed and less than 2% cross-reactivity with rhFGF acidic, rhFGF basic, rhFGF‑4, rhFGF‑5, rhFGF‑6, rhFGF‑7, rhFGF‑10, and rhFGF‑18 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for FGF-17 Antibody [DyLight 405]

Application

Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: FGF-17

The FGF17 gene codes for a fibroblast growth factor 17 protein that in isoform 1 is 216 amino acids long at 24 kDA and in isoform 2 is 205 amino acids long at 23 kDA. This gene is a member of the fibroblast growth factor (FGF) family so is thought to participate in nervous system development and function, specifically in embryonic development as well as a signaling molecule in the induction and patterning of the embryonic brain. FGF14 is involved in regulation of actin cytoskeleton, MAPK signaling, signaling by FGFR and FGFR mutants, as well as downstream signal transduction. It interacts with genes EGFR, FGFR1, FGFR2, FGFR3, and FGFR4. FGF14 is associated with pancreatitis, breast cancer, leukemia, melanoma, and adenocarcinoma.

Long Name

Fibroblast Growth Factor 17

Alternate Names

FGF17

Gene Symbol

FGF17

Additional FGF-17 Products

Product Documents for FGF-17 Antibody [DyLight 405]

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Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for FGF-17 Antibody [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

FGF Family

FGF Ligands

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