FGF-23 (fibroblast growth factor 23) is one of three FGF family members that appear to play a role in endocrine metabolism. It is described as being a phosphatonin, a molecule that reduces circulating plasma phosphate. FGF-23 does this, in part, by blocking Vitamin D activation. Active Vitamin D promotes intestinal phosphate absorption.
FGF-23 Antibody
Novus Biologicals | Catalog # NBP2-27553
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Key Product Details
Species Reactivity
Validated:
Mouse
Predicted:
Rat (100%). Backed by our 100% Guarantee.
Applications
Western Blot, Peptide ELISA
Label
Unconjugated
Antibody Source
Polyclonal Goat IgG
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Product Specifications
Immunogen
Peptide with sequence C-ENGYDVYLSQKHH corresponding to internal region according to NP_073148.1.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Description
Novus Biologicals Goat FGF-23 Antibody (NBP2-27553) is a polyclonal antibody validated for use in WB and ELISA. Anti-FGF-23 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
Scientific Data Images for FGF-23 Antibody
Western Blot: FGF-23 Antibody [NBP2-27553]
Western Blot: FGF-23 Antibody [NBP2-27553] - Staining of Mouse Testes lysate 1 (A) and Testes lysate 2 (B) + peptide (C) (35 ug protein in RIPA buffer). Antibody at 1 ug/mL. Detected by chemiluminescence.Applications for FGF-23 Antibody
Application
Recommended Usage
Peptide ELISA
Detection limit 1:128000
Western Blot
0.3 - 1 ug/mL
Application Notes
Western blot: Approx 27 kDa band observed in Mouse Testis lysates (calculated MW of 27.7 kDa according to NP_073148.1). Some lysates showed prominent bands at approx. 24+38 kDa which were successfully blocked by incubation with the immunizing peptide and have been reported in the literature (Garringer et al,. 2008, PMID:18682534).
Formulation, Preparation, and Storage
Purification
Immunogen affinity purified
Formulation
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C. Avoid freeze-thaw cycles.
Background: FGF-23
Long Name
Fibroblast Growth Factor 23
Alternate Names
FGF23
Gene Symbol
FGF23
UniProt
Additional FGF-23 Products
Product Documents for FGF-23 Antibody
Product Specific Notices for FGF-23 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
Citations for FGF-23 Antibody
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