Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Polyclonal Goat IgG
View all FGFR5/FGFRL1 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FGF R5/FGFRL1
Ala25-Pro378
Accession # Q8N441

Specificity

Detects human FGF R5/FGFRL1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 65% cross‑reactivity with recombinant mouse (rm) FGF R5 and rmFGF R5 beta is observed and less than 1% cross-reactivity with recombinant human (rh) FGF R1 alpha  (IIIb), rhFGF R1 alpha  (IIIc), rhFGF R1 beta  (IIIb), rhFGF R1 beta  (IIIc), rhFGF R2 alpha  (IIIb), rhFGF R2 alpha  (IIIc), rhFGF R2 beta  (IIIb), rhFGF R2 beta  (IIIc), rhFGF R3 alpha  (IIIb), rhFGF R3 (IIIc), and rhFGF R4 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for FGFR5/FGFRL1 Antibody [DyLight 405]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: FGFR5/FGFRL1

FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGFR1 through 5. FGFRs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGFR1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGFR5 does not. Multiple forms of FGFR1, 2, and 3 are generated by alternative splicing.

Long Name

Fibroblast Growth Factor Receptor-like 1

Alternate Names

FGF R5, FGFRL1

Gene Symbol

FGFRL1

Additional FGFR5/FGFRL1 Products

Product Documents for FGFR5/FGFRL1 Antibody [DyLight 405]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for FGFR5/FGFRL1 Antibody [DyLight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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