Fibrinogen gamma chain Antibody

Name: Fibrinogen gamma chain Antibody
Brand: Novus Biologicals
SKU: NBP2-42497
Price: 419 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-42497

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

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Product Specifications

Immunogen

Peptide with sequence C-QDIANKGAKQS corresponding to internal region according to NP_000500.2, NP_068656.2.

Specificity

This antibody is expected to recognize both reported isoforms (NP_000500.2; NP_068656.2).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Fibrinogen gamma chain Antibody

Western Blot: Fibrinogen gamma chain Antibody [NBP2-42497]

Western Blot: Fibrinogen gamma chain Antibody [NBP2-42497] - Analysis of human Plasma (A) and Platelets (B) lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Fibrinogen gamma chain Antibody

Application

Recommended Usage

Peptide ELISA

Detection limit 1:64000

Western Blot

0.1 - 0.3 ug/ml

Application Notes

WB: Approx. 50 kDa band observed in human plasma and human platelets lysates (calculated MW of 49.5 kDa band according to NP_000500.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Fibrinogen gamma chain

The protein encoded by the Fibrinogen gamma chain gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Alternate Names

fibrinogen gamma chain, fibrinogen, gamma polypeptide

Entrez Gene IDs

2266 (Human)

Gene Symbol

FGG

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Certificate of Analysis

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Product Specific Notices for Fibrinogen gamma chain Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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