Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Polyclonal Sheep IgG
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Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Fibromodulin/FMOD
Asp75-Ile376
Accession # Q06828

Specificity

Detects human, mouse, and rat Fibromodulin/FMOD in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Fibromodulin/FMOD Antibody [FITC]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Fibromodulin/FMOD

FMOD, also known as Fibromodulin, is a 376 amino acid protein that is 43 kDa, affects the rate of fibrils formation and may have a primary role in collagen fibrillogenesis and regulation of TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Current research is being performed on several diseases and disorders including refractive error, chronic lymphocytic leukemia, myopia, osteoarthritis, arthritis, cleft lip/palate, age related macular degeneration, pseudoachondroplasia, periodontitis, mantle cell lymphoma, chondrodysplasia, diabetic nephropathy, vaginitis, leiomyoma, essential hypertension, atherosclerosis, hypochondrogenesis, and Kniest dysplasia. This protein has also shown an interaction with TGFB1, TGFB2 and TGFB3 in Metalloproteases in connective tissue degradation, metabolism, MPS VI - Maroteaux-Lamy syndrome, disease, keratan sulfate/keratin metabolism, and MPS IIIA - Sanfilippo syndrome A pathways.

Alternate Names

FM, FMOD, SLRR2E

Gene Symbol

FMOD

Additional Fibromodulin/FMOD Products

Product Documents for Fibromodulin/FMOD Antibody [FITC]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Fibromodulin/FMOD Antibody [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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Associated Pathways

Articular Cartilage Extracellular Matrix Articular Cartilage Extracellular Matrix Thumbnail