FIG4 Antibody (SR2515)

Novus Biologicals | Catalog # NBP3-27791

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2515 expressed in HEK293
View all FIG4 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human FIG4 (Uniprot #: Q92562)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

104 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FIG4 Antibody (SR2515)

Western Blot: FIG4 Antibody (SR2515) [NBP3-27791] -

Western Blot: FIG4 Antibody (SR2515) [NBP3-27791] - Western blot analysis of FIG4 in HL-60, U2OS, U87-MG lysates

Applications for FIG4 Antibody (SR2515)

Application
Recommended Usage

Immunoprecipitation

1:20

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FIG4

The protein encoded by the FIG4 gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. (provided by RefSeq)

Alternate Names

ALS11polyphosphoinositide phosphatase, CMT4J, dJ249I4.1, EC 3.1.3, EC 3.1.3.-, EC 3.1.3.36, FIG4 homolog (S. cerevisiae), FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae), hSac3, KIAA0274FIG4 homolog, SAC domain containing lipid phosphatase, Phosphatidylinositol 3,5-bisphosphate 5-phosphatase, Sac domain-containing inositol phosphatase 3, SAC domain-containing protein 3, SAC3FIG4 homolog, SAC1 domain containing lipid phosphatase

Gene Symbol

FIG4

Additional FIG4 Products

Product Documents for FIG4 Antibody (SR2515)

Certificate of Analysis

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Product Specific Notices for FIG4 Antibody (SR2515)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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