Flavopiridol hydrochloride

  ( 1 citations )    
Product Datasheet
Catalog Number:3094
Alternate Names:L 86-8275
Chemical Name:2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one hydrochloride
Product Details
Citations (1)
Reviews
Biological Activity
Cyclin-dependent kinase (CDK) inhibitor that causes cell cycle arrest at G1 and G2 phase. Potently inhibits the growth of breast and lung cancer cell lines (IC50 = 25 - 160 nM) in vitro.
Technical Data
  • M.Wt:
    438.3
  • Formula:
    C21H20ClNO5.HCl
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    131740-09-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Flavopiridol hydrochloride include:

1 Citations: Showing 1 - 1

  1. Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage.
    Authors: Stork Et al.
    Elife  2016;5

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