FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit

R&D Systems | Catalog # FC012

R&D Systems
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Key Product Details

Species

Human, Mouse, Rat

Applications

Flow Cytometry

Formulation, Preparation, and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: FoxP3

Human FOXP3 is a 47 kDa member of the P subclass of the forkhead box family of transcription factors. It contains a Leu-rich repeat, a C2H2 zinc finger region, and a C-terminal FKH (forkhead) DNA-binding domain. In human, FOXP3 is found in CD4+, CD8+ and CD4+CD25+ T cells and directly associates with NFAT and NFkB, suppressing their activity in CD4+ T cells.

Long Name

Forkhead Box P3

Alternate Names

AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID

Entrez Gene IDs

50943 (Human); 20371 (Mouse)

Gene Symbol

FOXP3

Additional FoxP3 Products

Product Documents for FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit

For research use only

⚠ WARNING: This product can expose you to chemicals including formaldehyde and methanol, which are known to the State of California to cause cancer and reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov.

Citations for FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit

Customer Reviews for FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit (2)

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  • FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit
    Name: Anonymous
    Verified Customer | Posted 01/19/2024
    We utilized an antibody targeting nuclear proteins, making fixation and permeabilization necessary steps in the process.
    FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit FC012
  • FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit
    Name: Leslie Priddy
    Verified Customer | Posted 04/01/2018

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