FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit

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Product Details
Citations (2)
Reviews (2)

FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit Summary


Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Flow Cytometry
Human Mouse Rat

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Background: FoxP3

Human FOXP3 is a 47 kDa member of the P subclass of the forkhead box family of transcription factors. It contains a Leu-rich repeat, a C2H2 zinc finger region, and a C-terminal FKH (forkhead) DNA-binding domain. In human, FOXP3 is found in CD4+, CD8+ and CD4+CD25+ T cells and directly associates with NFAT and NFkB, suppressing their activity in CD4+ T cells.

Long Name
Forkhead Box P3
Entrez Gene IDs
50943 (Human); 20371 (Mouse)
Alternate Names
AIID; AIIDMGC141961; DIETER; forkhead box P3; Forkhead Box Protein P3; FoxP3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked; IPEX; JM2; MGC141961; MGC141963; PIDX; PIDXMGC141963; SCURFIN; XPID; XPIDpolyendocrinopathy, enteropathy, X-linked
⚠ WARNING: This product can expose you to chemicals including formaldehyde and methanol, which are known to the State of California to cause cancer and reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov.

Citations for FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Alteration of oxidative-stress and related marker levels in mouse colonic tissues and fecal microbiota structures with chronic ethanol administration: Implications for the pathogenesis of ethanol-related colorectal cancer
    Authors: H Ohira, A Tsuruya, D Oikawa, W Nakagawa, R Mamoto, M Hattori, T Waki, S Takahashi, Y Fujioka, T Nakayama
    PLoS ONE, 2021-02-12;16(2):e0246580.  2021-02-12
  2. Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
    Authors: Y Tian, M Babor, J Lane, V Schulten, VS Patil, G Seumois, SL Rosales, Z Fu, G Picarda, J Burel, J Zapardiel-, RN Tennekoon, AD De Silva, S Premawansa, G Premawansa, A Wijewickra, JA Greenbaum, P Vijayanand, D Weiskopf, A Sette, B Peters
    Nat Commun, 2017-11-13;8(1):1473.  2017-11-13


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Reviews for FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit

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FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit
By Anonymous on 01/19/2024

We utilized an antibody targeting nuclear proteins, making fixation and permeabilization necessary steps in the process.

FlowX FoxP3/Transcription Factor Fixation & Perm Buffer Kit
By Leslie Priddy on 04/01/2018