Biological Activity Selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.
(Modifications: Tyr-6 = C-terminal amide)
Soluble to 1 mg/ml in water
Store at -20°C
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