FSLLRY-NH2

  ( 5 citations )    
Product Datasheet
Catalog Number:4751
Chemical Name:
Product Details
Citations (5)
Supplemental Products
Reviews
Biological Activity
Selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.
Technical Data
  • M.Wt:
    796.97
  • Formula:
    C39H60N10O8
  • Sequence:
    FSLLRY-NH2

    (Modifications: Tyr-6 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    245329-02-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for FSLLRY-NH2 include:

5 Citations: Showing 1 - 5
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  1. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2
    Authors: Peng Et al.
    Phil. Trans. R. Soc. B  2016;371:1700
  2. A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p.
    Authors: White Et al.
    Cell Death Dis  2015;194:142
  3. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells.
    Authors: Tripathi Et al.
    Invest Ophthalmol Vis Sci  2014;55:3912
  4. Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases.
    Authors: Eum Et al.
    Am J Physiol Gastrointest Liver Physiol  2014;306:G992
  5. PAR2-mediated upregulation of BDNF contributes to central sensitization in bone cancer pain.
    Authors: Bao Et al.
    Mol Pain  2014;10:28

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