Home / Protease-Activated Receptor Antagonists / FSLLRY-NH2

FSLLRY-NH2

4751 6 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4751/1
FSLLRY-NH2
1 Image
Description: PAR2 peptide antagonist

Purity: ≥95%

Product Details
Citations (6)
Supplemental Products
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

FSLLRY-NH2 is a selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.

Technical Data

M.Wt:
796.97
Formula:
C39H60N10O8
Sequence:
FSLLRY

(Modifications: Tyr-6 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
245329-02-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

COA view current batch
Or select another batch:
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for FSLLRY-NH2

The citations listed below are publications that use Tocris products. Selected citations for FSLLRY-NH2 include:

6 Citations: Showing 1 - 6

  1. Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation.
    Authors: Noskovičová Et al.
    Am J Physiol Lung Cell Mol Physiol  2018;314:L695
  2. Calcium and adenosine triphosphate control of cellular pathology: asparaginase-induced pancreatitis elicited via protease-activated receptor 2
    Authors: Peng Et al.
    Phil. Trans. R. Soc. B  2016;371:1700
  3. A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p.
    Authors: White Et al.
    Cell Death Dis  2015;194:142
  4. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells.
    Authors: Tripathi Et al.
    Invest Ophthalmol Vis Sci  2014;55:3912
  5. Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases.
    Authors: Eum Et al.
    Am J Physiol Gastrointest Liver Physiol  2014;306:G992
  6. PAR2-mediated upregulation of BDNF contributes to central sensitization in bone cancer pain.
    Authors: Bao Et al.
    Mol Pain  2014;10:28

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

VersaClone cDNA Plasmids

Human PAR2 (NP_005233) VersaClone cDNA

RDC0166

Mouse PAR2 (NP_032000) VersaClone cDNA

RDC0167
1 Citations

Reviews for FSLLRY-NH2

There are currently no reviews for this product. Be the first to review FSLLRY-NH2 and earn rewards!

Have you used FSLLRY-NH2?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.