Key Product Details

Species Reactivity

Human

Applications

ELISA, Neutralization

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 743835
View all GDF-11/GDF-8 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human GDF-11/BMP-11
Asn299-Ser407
Accession # O95390

Specificity

Detects human GDF-11/BMP-11 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with mouse GDF-8 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for GDF-11/GDF-8 Antibody (743835) [DyLight 405]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GDF-11/GDF-8

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]

Long Name

Growth Differentiation Factor 11/8

Alternate Names

BMP11, BMP-11, bone morphogenetic protein 11, GDF-11, growth/differentiation factor 11, VHO

Gene Symbol

GDF11

Additional GDF-11/GDF-8 Products

Product Documents for GDF-11/GDF-8 Antibody (743835) [DyLight 405]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for GDF-11/GDF-8 Antibody (743835) [DyLight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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