Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 7C12.B3.F2
View all GDF-15 Primary Antibodies »

Product Specifications

Immunogen

This Protein A purified GDF-15 Antibody (7C12.B3.F2) was prepared by repeated immunizations with a synthetic peptide corresponding to a region near the amino terminal end of human GDF-15 protein. A residue of cysteine was added to facilitate coupling to KLH. (Uniprot: Q99988)

Reactivity Notes

A BLAST analysis was used to suggest partial reactivity with GDF-15 from chimpanzee and macaque based on a 92% homology. Cross-reactivity with GDF-15 from other sources has not been determined.

Specificity

This antibody specifically reacts with an H variant sequence of human GDF-15 protein from human tissues.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for GDF-15 Antibody (7C12.B3.F2) [PE]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GDF-15

Growth differentiation factor 15 (GDF15) is a transforming growth factor beta superfamily member that acts to regulate inflammatory and apoptotic responses in injured or diseased tissues. GDF15 is most strongly expressed in the liver, placenta and kidney.

GDF15 antibodies are useful for studies on inflamation and immune system research.

Long Name

Growth Differentiation Factor 15

Alternate Names

GDF15, MIC-1, NAG-1, PDF, PLAB, PTGF-beta

Gene Symbol

GDF15

Additional GDF-15 Products

Product Documents for GDF-15 Antibody (7C12.B3.F2) [PE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for GDF-15 Antibody (7C12.B3.F2) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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