Human Geminin ELISA Kit (Colorimetric)

Novus Biologicals | Catalog # NBP2-60570

Novus Biologicals
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Key Product Details

Sample Type & Volume Required Per Well

Serum, Plasma, Cell Culture

Sensitivity

0.01 ng/ml (example only; lot dependent)

Assay Range

0.0156 - 1 ng/ml (example only; lot dependent)
View all Geminin ELISA Kits »

Product Specifications

Assay Type

Sandwich ELISA

Kit Type

ELISA Kit (Colorimetric)

Species

Human

Description

This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.

Precision

Intra-Assay Precision (Precision within an assay) CV% 4.20% (example only; lot dependent)

Inter-Assay Precision (Precision between assays) CV% 7.40% (example only; lot dependent)

Recovery for Human Geminin ELISA Kit (Colorimetric)

Recovery

96.00% (example only; lot dependent)

Scientific Data Images for Human Geminin ELISA Kit (Colorimetric)

ELISA: Human Geminin ELISA Kit (Colorimetric) [NBP2-60570]

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Geminin

Geminin is a multifunctional nuclear protein invloved in embyro development/differentiation, cell cycle regulation and DNA replciation. Originally defined as an inhibitor of DNA replication and substrate of the anaphase promoting complex, Geminin has also been shown to expand the neural plate in the developing embryos.

Geminin prevents DNA replication by blocking the MCM complex incorporation into prereplication complex (pre-RC). It is absent during the G1 phase and accumulates during the S, G2, and M phases of mitosis. Geminin is then degraded during the metaphase-anaphase trasitio,n allowing replication to occur during subsequent cycles.

Geminin antibodies are useful tools for a variety of research including developmental embryology, stem cell differentiation, neuroscience, and DNA replication studies.

Alternate Names

Gem, geminin, geminin, DNA replication inhibitor, RP3-369A17.3

Gene Symbol

GMNN

Additional Geminin Products

Product Documents for Human Geminin ELISA Kit (Colorimetric)

Certificate of Analysis

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Product Specific Notices for Human Geminin ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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