Gephyrin/GPHN Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-29143

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Gephyrin/GPHN Primary Antibodies »

Product Specifications

Immunogen

Between 250 and 300

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Gephyrin/GPHN Antibody - BSA Free

Gephyrin/GPHN Antibody

Immunoprecipitation:Gephyrin/GPHN AntibodyNBP3-29143] -

Immunoprecipitation:Gephyrin/GPHN AntibodyNBP3-29143] -Detection of human Gephyrin by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-Gephyrin antibody NBP3-29143 (lot NBP3-29143-1) used for IP at 6 µg/mg lysate. Gephyrin was also immunoprecipitated by rabbit anti-Gephyrin antibody BL15657. For blotting immunoprecipitated Gephyrin, NBP3-29143 was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

Applications for Gephyrin/GPHN Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Gephyrin/GPHN

The Gephyrin (GPHN) gene encodes a neuronal assembly protein that exists in isoform 1 (736 amino acids long, 79 kDA) or isoform 2 (769 amino acids in length, approximately 83 kDA). This protein anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton through high affinity binding to a receptor subunit domain and tublin dimers. The protein coded by GPHN is also necessary for molybdenum biosynthesis. The GPHN gene has been investigated in relation to many diseases such as leukemia, cervicitis, tuberculosis, alzheimer's disease, anorexia nervosa, huntington's disease, retinitis, and herpes zoster. The GPHN gene interacts with genes DYNLL1, PFN1, PRPF4, ENAH, and SLX4 to participate in pathways that regulate metabolism of vitamins and cofactors as well as molybdenum cofactor biosynthesis.

Alternate Names

GEPH, GPH, GPHN, GPHRYN

Gene Symbol

GPHN

Additional Gephyrin/GPHN Products

Product Documents for Gephyrin/GPHN Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Gephyrin/GPHN Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

GABA Receptors
Neuronal Markers

Customer Reviews for Gephyrin/GPHN Antibody - BSA Free

There are currently no reviews for this product. Be the first to review Gephyrin/GPHN Antibody - BSA Free and earn rewards!

Have you used Gephyrin/GPHN Antibody - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies