Home / Dehydrogenase Inhibitors / Gliocidin

Gliocidin

Catalog #: 8893 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8893/50
8893/10

Save 15% on Select RUO Reagents. See Details. 

Gliocidin | CAS No. 62289-81-0 | Dehydrogenase Inhibitors
1 Image
Description: IMPDH2 (inosine monophosphate dehydrogenase 2) inhibitor, also glioblastoma targeting Nicotinamide mimetic prodrug

Chemical Name: N-3-Pyridinyl-2-thiophenecarboxamide

Purity: ≥98%

Product Details
Reviews
Biological Activity Technical Data Product Datasheets Calculators

Biological Activity

Gliocidin is an IMPDH2 (inosine monophosphate dehydrogenase 2) inhibitor. Gliocidin is a nicotinamide-mimetic prodrug that is anabolized into its tumoricidal metabolite, gliocidin-adenine dinucleotide (GAD). Gliocidin kills glioblastoma cells while sparing non-tumour replicative cells. In vivo, Gliocidin penetrates the blood-brain barrier and extends the survival of mice with orthotopic glioblastoma.

Technical Data

M.Wt:
204.25
Formula:
C10H8N2OS
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
62289-81-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Gliocidin

There are currently no reviews for this product. Be the first to review Gliocidin and earn rewards!

Have you used Gliocidin?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.