GluR5/GRIK1 Antibody

Name: GluR5/GRIK1 Antibody
Brand: Novus Biologicals
SKU: NBP3-12471
Price: 439 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-12471

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Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Mouse, Rat

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

View all GluR5/GRIK1 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to unique amino acid region on GluR5.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for GluR5/GRIK1 Antibody

Western Blot: GluR5/GRIK1 Antibody [NBP3-12471]

Western Blot: GluR5/GRIK1 Antibody [NBP3-12471] - 1:500 antibody dilution in DiluObuffer. Apparent MW is 117 KDa.

Applications for GluR5/GRIK1 Antibody

Application

Recommended Usage

ELISA

1:10000

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: GluR5/GRIK1

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brain stem whereas the four epsilon subunits display limited distribution.

Long Name

Glutamate Receptor 5

Alternate Names

EAA3, EEA3, GluK1, GRIK1

Gene Symbol

GRIK1

Additional GluR5/GRIK1 Products

Product Documents for GluR5/GRIK1 Antibody

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Certificate of Analysis

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Product Specific Notices for GluR5/GRIK1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Neurotransmitter G Protein-Coupled Receptors

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